Weill Cornell Bone Marrow Transplant Program

Allogeneic Transplantation for Patients With Advanced Myelofibrosis: Splenomegaly and High Serum LDH are Adverse Risk Factors for Successful Engraftment

Leave a comment

Myelofibrosis is an often aggressive form of myeloproliferative disease. Many patients benefit from medical therapy, but others are better served with a stem cell transplantation. Dr. Usama Gergis from our team recently reported the outcomes for 30 patients transplanted at our institution between 2000 and 2014. He showed that long term cure can be obtained, but that the risks are considerable, particularly in patients with massive splenomegaly.


These historical data are informative, but are unlikely to represent current outcomes.  Better supportive care and earlier referral have over the past years resulted in markedly improved outcomes.


Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s